ALPHARONA(injectable)

Состав: Active substance: Interferon alpha-2b human recombinant - 500000 IU, 1000000 IU, 3000000 IU, 5000000 IU. Excipients: polyglucin, sodium chloride, sodium dihydrogen phosphate, disodium hydrogen phosphate.
Released
prescription
Keep
in a refrigerator
About the preparation
Antiviral, antitumor agent. Has antiviral, antitumor, immunomodulating activity.

Used in combined therapy of adults:

  • acute viral hepatitis В - moderate and severe forms at the beginning of icteritous period;
  • acute prolonged hepatitis В, chronic active viral hepatitis В and D, hepatitis С;
  • encephalomeningitis: viral, viral and bacterial, mycoplasmal;
  • viral conjunctivitis, keratoconjunctivitis, keratitis, keratouveitis;
  • stage IV kidney cancer, hairy-cell leukemia, malignant skin lymphadenosis, Kaposi's sarcoma, basal cell and squamous cell carcinoma of the skin, keratoacanthoma, chronic myelogenous leukemia, histiocytosis-X, subleukemic myelosis, essential thrombocytopenia;
  • disseminated sclerosis.
In combined therapy of children:
  • acute lymphoblastic leucosis in remission period;
  • respiratory laryngeal papillomatosis.
Form of release, composition and packaging
Lyophilizate for preparation of solution for injections and local application 500,000 IU, 1,000,000 IU, 3,000,000 IU, 5,000,000 IU of active ingredient per 1 vial. 1, 5,10 or 20 vials of the drug with application instructions are put into cardboard package or 1, 5,10 or 20 vials of the drug in contour cellular package or in cassette contour package with application instructions are put into cardboard package.
Indications for use
In combined therapy of adults:
  • for acute viral hepatitis В
  • moderate and severe forms in the beginning of icteritous period up to the 5th day of icterus (later administration of the drug is less effective; it is not effective for developing hepatic coma and cholestatic course of disease);
  • for acute prolonged hepatitis B, chronic active hepatitis В and D without signs of cirrhosis and when signs of hepatic cirrhosis appear;
  • for chronic viral hepatitis C;
  • for viral (influenza-like, adenoviral, enteroviral, herpetic, parotitic), viral and bacterial and mycoplasmal encephalomeningitis. Drug administration is the most efficient in the first 4 days of the disease;
  • for viral conjunctivitis, keratoconjunctivitis, keratitis, keratouveitis;
  • for stage IV kidney cancer, hairy-cell leukemia, malignant skin lymphadenosis (mycosis fungoidea, polymorphic reticulosis), Kaposi's sarcoma, basal cell and squamous cell carcinoma of the skin, keratoacanthoma, chronic myelogenous leukemia, histiocytosis-X, subleukemic myelosis, essential thrombocytopenia;
  • for disseminated sclerosis.
In combined therapy of children:
  • for acute lymphoblastic leucosis in remission period after completion of inductive chemotherapy (in 4-5 months of remission);
  • for respiratory laryngeal papillomatosis, starting from the day following papilloma removal.
Contraindications
Severe forms of allergic diseases; pregnancy.
Other drugs
АЛЬФАРОНА (интерферон альфа-2b, 500 000 ME, 1 000 000 МЕ, 3 000 000 ME, 5 000 000 ME). 
В комплексной терапии у взрослых: 
  • острый вирусный гепатит В - среднетяжелые и тяжелые формы в начале желтушного периода;
  • острый затяжной гепатит В, хронический активный вирусный гепатит В и D, гепатит С;
  • менингоэнцефалиты: вирусные, вирусно-бактериальные, микоплазменные;
  • вирусные конъюнктивиты, кератоконъюнктивиты, кератиты, кератоувеиты;
  • рак почки IV стадии, волосатоклеточный лейкоз, злокачественные лимфомы кожи, саркома Капоши, базально-клеточный и плоскоклеточный рак кожи, кератоактанома, хронический миелолейкоз, гистиоцитоз-Х, сублейкемический миелоз, эссенциальная тромбоцитопения; рассеянный склероз.